Comparative assessment of efficacy and withdrawal symptoms after 6 and 12 weeks' treatment with diazepam or buspirone.

@article{Murphy1989ComparativeAO,
  title={Comparative assessment of efficacy and withdrawal symptoms after 6 and 12 weeks' treatment with diazepam or buspirone.},
  author={S. Murphy and R. Owen and P. Tyrer},
  journal={The British journal of psychiatry : the journal of mental science},
  year={1989},
  volume={154},
  pages={
          529-34
        }
}
  • S. Murphy, R. Owen, P. Tyrer
  • Published 1989
  • Medicine, Psychology
  • The British journal of psychiatry : the journal of mental science
  • Fifty-one out-patients presenting with generalised anxiety disorder were included in a double-blind trial, and treated with either buspirone (a new non-benzodiazepine antianxiety drug) or diazepam over 6 or 12 weeks, after which they were abruptly withdrawn and continued on placebo to 14 weeks. Ratings of anxiety and other symptoms were administered fortnightly and additional withdrawal symptoms noted. Forty patients completed the study; 8 of the 11 drop-outs were taking buspirone. Both drugs… CONTINUE READING

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