Comparative antimycobacterial activities of ofloxacin, ciprofloxacin and grepafloxacin.

  title={Comparative antimycobacterial activities of ofloxacin, ciprofloxacin and grepafloxacin.},
  author={Sylvette Wiener Vacher and J. L. Pellegrin and Francis R LeBlanc and Jacques Fourche and Jeanne Maugein},
  journal={The Journal of antimicrobial chemotherapy},
  volume={44 5},
Infections caused by non-tuberculous mycobacteria and multidrug-resistant Mycobacterium tuberculosis are difficult to treat. New compounds potentially active against these bacteria are therefore constantly being sought. Among them is grepafloxacin, a new C5 fluoroquinolone. A panel of 130 isolates of mycobacteria including 33 M. tuberculosis isolates and 97 isolates of different species of atypical mycobacteria were analysed for susceptibility to grepafloxacin, ofloxacin and ciprofloxacin. The… CONTINUE READING