Comparative and quantitative proteomic analysis of normal and degenerated human annulus fibrosus cells

@article{Ye2015ComparativeAQ,
  title={Comparative and quantitative proteomic analysis of normal and degenerated human annulus fibrosus cells},
  author={Dongping Ye and Weiguo Liang and L. Dai and Longqiang Zhou and Yicun Yao and X. Zhong and Hong-hui Chen and J. Xu},
  journal={Clinical and Experimental Pharmacology and Physiology},
  year={2015},
  volume={42}
}
  • Dongping Ye, Weiguo Liang, +5 authors J. Xu
  • Published 2015
  • Biology, Medicine
  • Clinical and Experimental Pharmacology and Physiology
  • Degeneration of the intervertebral disc (IVD) is a major chronic medical condition associated with back pain. To better understand the pathogenesis of IVD degeneration, we performed comparative and quantitative proteomic analyses of normal and degenerated human annulus fibrosus (AF) cells and identified proteins that are differentially expressed between them. Annulus fibrosus cells were isolated and cultured from patients with lumbar disc herniation (the experimental group, degenerated AF cells… CONTINUE READING
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    References

    SHOWING 1-10 OF 29 REFERENCES
    Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs
    • 316
    • Highly Influential
    • PDF
    Histology and pathology of the human intervertebral disc.
    • 569
    • PDF