Comparative and evolutionary studies of vertebrate ALDH1A-like genes and proteins.

@article{Holmes2015ComparativeAE,
  title={Comparative and evolutionary studies of vertebrate ALDH1A-like genes and proteins.},
  author={Roger S. Holmes},
  journal={Chemico-biological interactions},
  year={2015},
  volume={234},
  pages={4-11}
}
Vertebrate ALDH1A-like genes encode cytosolic enzymes capable of metabolizing all-trans-retinaldehyde to retinoic acid which is a molecular 'signal' guiding vertebrate development and adipogenesis. Bioinformatic analyses of vertebrate and invertebrate genomes were undertaken using known ALDH1A1, ALDH1A2 and ALDH1A3 amino acid sequences. Comparative analyses… CONTINUE READING