• DOI:10.1016/S0888-7543(05)80224-1
Corpus ID: 6393404

Comparative anatomy of the primate major histocompatibility complex DR subregion: evidence for combinations of DRB genes conserved across species.

@article{Kasahara1992ComparativeAO,
  title={Comparative anatomy of the primate major histocompatibility complex DR subregion: evidence for combinations of DRB genes conserved across species.},
  author={M. Kasahara and D. Klein and V. Vincek and D. Sarapata and J. Klein},
  journal={Genomics},
  year={1992},
  volume={14 2},
  pages={
          340-9
        }
}

M. Kasahara, D. Klein, +2 authors J. Klein

Published 1992

Biology, Medicine

Genomics

The class II region of the human major histocompatibility complex (HLA) is made up of three major subregions designated DR, DQ, and DP. With the aim of gaining an insight into the evolution and stability of DR haplotypes, a total of 63 cosmid clones were isolated from the DR subregion (Gogo-DR) of a western lowland gorilla. All but one of these cosmid clones were found to fall into two clusters. The larger cluster, A, was defined by 41 overlapping cosmid clones and contained a DRB gene segment… CONTINUE READING

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