Comparative analysis of the virulence of invertebrate and mammalian pathogenic bacteria in the oral insect infection model Galleria mellonella.

@article{Fedhila2010ComparativeAO,
  title={Comparative analysis of the virulence of invertebrate and mammalian pathogenic bacteria in the oral insect infection model Galleria mellonella.},
  author={Sinda Fedhila and Christophe Buisson and Olivier Dussurget and Pascale Serror and Ian Justin Glomski and Peter Liehl and Didier Lereclus and Christina Nielsen-Leroux},
  journal={Journal of invertebrate pathology},
  year={2010},
  volume={103 1},
  pages={24-9}
}
Infection of Galleria mellonella by feeding a mixture of Bacillus thuringiensis spores or vegetative bacteria in association with the toxin Cry1C results in high levels of larval mortality. Under these conditions the toxin or bacteria have minimal effects on the larva when inoculated separately. In order to evaluate whether G. mellonella can function as an oral infection model for human and entomo-bacterial pathogens, we tested strains of Bacillus cereus, Bacillus anthracis, Enterococcus… CONTINUE READING

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