Comparative analysis of the quality of a global algorithm and a local algorithm for alignment of two sequences

@article{Polyanovsky2010ComparativeAO,
  title={Comparative analysis of the quality of a global algorithm and a local algorithm for alignment of two sequences},
  author={Valery Polyanovsky and Mikhail A. Roytberg and Vladimir G. Tumanyan},
  journal={Algorithms for Molecular Biology : AMB},
  year={2010},
  volume={6},
  pages={25 - 25}
}
BackgroundAlgorithms of sequence alignment are the key instruments for computer-assisted studies of biopolymers. Obviously, it is important to take into account the "quality" of the obtained alignments, i.e. how closely the algorithms manage to restore the "gold standard" alignment (GS-alignment), which superimposes positions originating from the same position in the common ancestor of the compared sequences. As an approximation of the GS-alignment, a 3D-alignment is commonly used not quite… 
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