Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells

@article{Feldbrgge2002ComparativeAO,
  title={Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells},
  author={Michael Feldbr{\"u}gge and P. Arizti and Michael L. Sullivan and phillip. zamore and Joel G. Belasco and Pamela J. Green},
  journal={Plant Molecular Biology},
  year={2002},
  volume={49},
  pages={215-223}
}
The labile SAUR transcripts from higher plants contain a conserved DST sequence in their 3′-untranslated regions. Two copies of a DST sequence from soybean are sufficient to destabilize reporter transcripts in cultured tobacco cells whereas variants bearing mutations in the conserved ATAGAT or GTA regions are inactive. To investigate the potential for conserved recognition components in mammalian and plant cells, we examined the function of this instability determinant in mouse NIH3T3… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 50 references

through a conserved domain that defines a new class of RNA - binding proteins

  • P. D. Zamore, D. P. Bartel, R. Lehmann, J. R. Williamson
  • 1999
1 Excerpt

Direct evidence for rapid degradation of Bacillus thuringiensis toxin mRNA as a cause of poor expression in plants

  • E. J. DeRocher, E. C. Vargo-Gogola, S. H. Diehn, P. J. Green
  • Plant Physiol. 117: 1445–1461.
  • 1998
2 Excerpts

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