Comparative analysis of the human dystrophin and utrophin gene structures.

  title={Comparative analysis of the human dystrophin and utrophin gene structures.},
  author={Uberto Pozzoli and Manuela Sironi and Rachele Cagliani and Giacomo Comi and Alessandra Bardoni and Nereo Bresolin},
  volume={160 2},
We present analysis of intronic sequences in the human DMD and UTRN genes. In both genes accumulation of repeated elements could account for intron expansion. Out-of-frame rod-domain exons have stronger splice sites and are separated by significantly longer introns as compared to in-frame exons. These features are unique for the two homologs and not shared by other spectrin superfamily genes. 

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