Comparative analysis of subgingival red complex bacteria in obese and normal weight subjects with and without chronic periodontitis

  title={Comparative analysis of subgingival red complex bacteria in obese and normal weight subjects with and without chronic periodontitis},
  author={Snophia Suresh and Jaideep Mahendra and Angabakkam Rajasekaran Pradeep Kumar and Gurdeep Singh and Selvaraj Jayaraman and Roshini Paul},
  journal={Journal of Indian Society of Periodontology},
  pages={186 - 191}
Background: Obesity is one of the systemic conditions which influence the onset and progression of periodontal disease and it is stated that the metabolic changes associated with obesity may contribute to alteration in subgingival microbial flora. Aim: Our study was aimed to quantify and compare the red complex microorganisms in obese or overweight and normal weight participants with and without chronic periodontitis to identify obesity as a risk for the presence of red complex bacteria… 

Tables from this paper

Subgingival microbiota in overweight and obese young adults with no destructive periodontal disease.
Fewperiodontal pathogens differed in levels between NW and OW/OB individuals without destructive periodontal disease, and the interaction of Prevotella spp.
Impact of non-surgical periodontal therapy on serum Resistin and periodontal pathogen in periodontitis patients with obesity
The impact of NSPT towards serum resistin and periodontal pathogens was non-significant in those with periodontitis, but obesity remained as a predictor for VPI and GBI after adjusting for smoking habit.
What Are the Clinical and Systemic Results of Periodontitis Treatment in Obese Individuals?
Overall, obese individuals with periodontitis can significantly benefit from non-surgical periodontal treatment, but clinical improvements seem to be less prominent in obese Individuals with Periodontitis compared to non-obese individuals with similarperiodontal status.
Comparative Assessment of P. gingivalis Level in Periodontit is Patients with and without Diabetes Mellitus- A PCR based Study
Poor glycemic control, as indicated by HbA1c≥7%, is associated with increased levels and frequencies of periodontal pathogens in the subgingival biofilm of subjects with DM.
Association between clinical measures of gingival inflammation and obesity in adults: systematic review and meta-analyses.
Clinicians must be aware that higher measures of gingival inflammation may be expected for individuals with higher BMI, and there is a necessity for further longitudinal studies regarding the association between obesity and gingingival inflammation.
Validity of the association between periodontitis and female infertility conditions: a concise review.
The available evidence on the association between periodontitis and female infertility-associated conditions is summarized, and warranting steps in future research are discussed.
It is suggested that periodontitis is likely to increase the risk of dementia, however, the amount and quality of evidence currently available is insufficient and of moderate to low quality to draw any firm conclusions.
The Association between Periodontal Disease and Obesity: Roles of the Dysbiotic Microbiome and Inflammation
It is claimed that the number of people affected by the infectious disease coronavirus in Europe has tripled in the past decade.


Relation of body mass index, periodontitis and Tannerella forsythia.
The data suggest that an overgrowth of T. forsythia occurs in the subgingival biofilms of periodontally healthy, overweight and obese individuals that might put them at risk for initiation and progression ofperiodontitis.
Comparative Analysis of GCF Resistin Levels in Obese Subjects with and without Periodontal Disease.
It is reported that obese subjects with periodontitis have more GCF resistin levels compared to non-obese subjects with healthy periodontium and this correlation was statistically significant.
Does obesity influence the subgingival microbiota composition in periodontal health and disease?
Obese patients with CP harboured higher levels and/or higher proportions of several periodontal pathogens than those with NW and CP, including Aggregatibacter actinomycetemcomitans, Eubacterium nodatum, Fusobacterium nucleatum ss vincentii, Parvimonas micra,Prevotella intermedia, Tannerella forsythia, Prevotella melaninogenica and Treponema socranskii.
Bacterial species in subgingival plaque and oral bone loss in postmenopausal women.
The prevalence of specific bacterial infections was determined for a large group of postmenopausal women and those with infection were more likely to have oral bone loss.
Obesity and periodontal disease in young, middle-aged, and older adults.
In a younger population, overall and abdominal obesity are associated with increased prevalence of periodontal disease, while underweight (BMI < 18.5) is associated with decreased prevalence.
Association between periodontal disease and overweight and obesity: a systematic review.
It is suggested that overweight, obesity, weight gain, and increased waist circumference may be risk factors for development of periodontitis or worsening ofperiodontal measures.
Oral microflora and periodontal disease: new technology for diagnosis in dentistry.
In the present study a real-time PCR based assay was designed to detect and quantify red complex species, then used to investigate 146 periodontal pocket samples from 66 periodontitis patients and 80 controls and demonstrated a significant higher prevalence of redcomplex species and increased amount of P. gingivalis and T. denticola in periodontAL pocket of periodontoitis patients.
Body Mass Index as a Predictive Factor of Periodontal Therapy Outcomes
BMI and obesity appear to be independent predictors of poor response following non-surgical periodontal therapy in patients with severe periodontitis, similar to that of smoking.
The novel association between red complex of oral microbe and body mass index in healthy Japanese: a population based cross-sectional study
Body mass index and waist circumference were independently associated with the number of red complex among apparently healthy Japanese, implying the possibility that oral microbe was associated with obesity in healthy population.
Association between overweight/obesity and increased risk of periodontitis.
Overweight/obese individuals are more likely to suffer from periodontitis compared to normal weight individuals in this case-control sample.