Comparative analysis of host responses related to immunosuppression between measles patients and vaccine recipients with live attenuated measles vaccines

@article{Okada2001ComparativeAO,
  title={Comparative analysis of host responses related to immunosuppression between measles patients and vaccine recipients with live attenuated measles vaccines},
  author={Haruhiko Okada and Takaya Sato and Ayako Katayama and Kiyohiro Higuchi and Kazuko Shichijo and Takatsugu Tsuchiya and Naohisa Takayama and Yasuhiro Takeuchi and Toshifumi Abe and Nobuhiko Okabe and Masato Tashiro},
  journal={Archives of Virology},
  year={2001},
  volume={146},
  pages={859-874}
}
  • Haruhiko Okada, Takaya Sato, +8 authors Masato Tashiro
  • Published in Archives of Virology 2001
  • Medicine, Biology
  • Summary. Measles virus infection induces a profound immunosuppression. We analyzed in a time-dependent manner peripheral bloods of one to two-year-old children immunized with live attenuated measles vaccines, compared with age-matched measles patients, for immunosuppression. In contrast to transient severe lymphopenia with measles patients, primarily due to extensive apoptosis of a broad spectrum of uninfected lymphocytes, neither apoptosis nor lymphopenia occurred with measles vaccine… CONTINUE READING

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