Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants.

@article{Vaccari2009ComparativeAO,
  title={Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants.},
  author={Thomas Vaccari and Tor Erik Rusten and Laurent Menut and Ioannis P. Nezis and Andreas Brech and Harald Stenmark and David Bilder},
  journal={Journal of cell science},
  year={2009},
  volume={122 Pt 14},
  pages={
          2413-23
        }
}
ESCRT proteins were initially isolated in yeast as a single functional set of conserved components controlling endosomal cargo sorting and multivesicular body (MVB) biogenesis. Recent work has suggested that metazoan ESCRT proteins might have more functionally diverse roles, but the limited availability of ESCRT mutants in species other than yeast has hampered a thorough analysis. Here, we used a genetic screening strategy based on both cell-autonomous and non-autonomous growth-promotion… CONTINUE READING

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Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2008