Comparative analysis of CRISPR loci in lactic acid bacteria genomes.

  title={Comparative analysis of CRISPR loci in lactic acid bacteria genomes.},
  author={Philippe Horvath and Anne-Claire Co{\^u}t{\'e}-Monvoisin and Dennis A. Romero and Patrick Boyaval and Christophe Fremaux and Rodolphe Barrangou},
  journal={International journal of food microbiology},
  volume={131 1},
Clustered regularly interspaced short palindromic repeats (CRISPR) are hypervariable loci widely distributed in bacteria and archaea, that provide acquired immunity against foreign genetic elements. Here, we investigate the occurrence of CRISPR loci in the genomes of lactic acid bacteria (LAB), including members of the Firmicutes and Actinobacteria phyla. A total of 102 complete and draft genomes across 11 genera were studied and 66 CRISPR loci were identified in 26 species. We provide a… CONTINUE READING


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