Comparative analysis detects dependencies among the 5' splice-site positions.

@article{Carmel2004ComparativeAD,
  title={Comparative analysis detects dependencies among the 5' splice-site positions.},
  author={Ido Carmel and Saar Tal and Ida Vig and Gil Ast},
  journal={RNA},
  year={2004},
  volume={10 5},
  pages={828-40}
}
Human-mouse comparative genomics is an informative tool to assess sequence functionality as inferred from its conservation level. We used this approach to examine dependency among different positions of the 5' splice site. We compiled a data set of 50,493 homologous human-mouse internal exons and analyzed the frequency of changes among different positions of homologous human-mouse 5' splice-site pairs. We found mutual relationships between positions +4 and +5, +5 and +6, -2 and +5, and -1 and… CONTINUE READING
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YIDB : the Yeast Intron DataBase

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