Comparative analyses of ubiquitin-like ATG8 and cysteine protease ATG4 autophagy genes in the plant lineage and cross-kingdom processing of ATG8 by ATG4.

@article{Seo2016ComparativeAO,
  title={Comparative analyses of ubiquitin-like ATG8 and cysteine protease ATG4 autophagy genes in the plant lineage and cross-kingdom processing of ATG8 by ATG4.},
  author={Eunyoung Seo and Jongchan Woo and Eunsook Park and Steven J Bertolani and Justin B. Siegel and Doil Choi and Savithramma P Dinesh-Kumar},
  journal={Autophagy},
  year={2016},
  volume={12 11},
  pages={
          2054-2068
        }
}
Autophagy is important for degradation and recycling of intracellular components. In a diversity of genera and species, orthologs and paralogs of the yeast Atg4 and Atg8 proteins are crucial in the biogenesis of double-membrane autophagosomes that carry the cellular cargoes to vacuoles and lysosomes. Although many plant genome sequences are available, the ATG4 and ATG8 sequence analysis is limited to some model plants. We identified 28 ATG4 and 116 ATG8 genes from the available 18 different… CONTINUE READING
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