Comparative analyses of B cell populations in trout kidney and mouse bone marrow: establishing "B cell signatures".

@article{Zwollo2010ComparativeAO,
  title={Comparative analyses of B cell populations in trout kidney and mouse bone marrow: establishing "B cell signatures".},
  author={Patty Zwollo and Katrina Mott and Maggie Barr},
  journal={Developmental and comparative immunology},
  year={2010},
  volume={34 12},
  pages={1291-9}
}
This study aimed to identify the frequency and distribution of developing B cell populations in the kidney of the rainbow trout, using four molecular B cell markers that are highly conserved between species, including two transcription factors, Pax5 and EBF1, recombination-activating gene RAG1, and the immunoglobulin heavy chain mu. Three distinct B cell stages were defined: early developing B cells (CLP, pro-B, and early pre-B cells), late developing B cell (late pre-B, immature B, and mature… CONTINUE READING