Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion

@article{Fu2008ComparativeAO,
  title={Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion},
  author={Xiao-Dong Fu and Maria Silvia Giretti and Lorenzo Goglia and Marina In{\'e}s Flamini and Angel Mat{\'i}as Sanchez and Chiara Baldacci and Silvia Garibaldi and R{\'e}gine L Sitruk-Ware and Andrea Riccardo Genazzani and Tommaso Simoncini},
  journal={BMC Cancer},
  year={2008},
  volume={8},
  pages={166 - 166}
}
Limited information is available on the effects of progestins on breast cancer progression and metastasis. Cell migration and invasion are central for these processes, and require dynamic cytoskeletal and cell membrane rearrangements for cell motility to be enacted. We investigated the effects of progesterone (P), medroxyprogesterone acetate (MPA), drospirenone (DRSP) and nestorone (NES) alone or with 17β-estradiol (E2) on T47-D breast cancer cell migration and invasion and we linked some of… CONTINUE READING