Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation.

@article{Barber2013ComparativeAO,
  title={Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation.},
  author={Elizabeth Barber and Andrew J E Sinclair and David Cameron-Smith},
  journal={Prostaglandins, leukotrienes, and essential fatty acids},
  year={2013},
  volume={89 5},
  pages={359-66}
}
Storage of fat into lipid droplets (LDs) is the key step in adipogenesis. Previously the omega-3 polyunsaturated fatty acid (n-3PUFA) eicosapentaenoic acid (EPA; C20:5n-3) has been shown to suppress LD formation, yet the actions of other n-3PUFA is unknown. Here, we examined the impact of the three major long chain n-3PUFA; EPA, docosapentaenoic acid (DPA; C22:5n-3) and docosahexaenoic acid (DHA; C22:6n-3) on LD formation in 3T3-L1 adipocytes. Cells were supplemented with 100µM fatty acid… CONTINUE READING

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Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Previously the omega-3 polyunsaturated fatty acid ( n-3PUFA ) eicosapentaenoic acid ( EPA ; C20:5n-3 ) has been shown to suppress LD formation , yet the actions of other n-3PUFA is unknown .
Gene ExpressionProcess includes biological processprotein expression
Furthermore , DHA significantly increased lipolysis and ATGL gene and protein expression but reduced the gene expression of three proteins related to LD formation ( Perilipin A , Caveolin-1 and Cidea ) , compared with other n-3PUFA .
Furthermore , DHA significantly increased lipolysis and ATGL gene and protein expression but reduced the gene expression of three proteins related to LD formation ( Perilipin A , Caveolin-1 and Cidea ) , compared with other n-3PUFA .
Furthermore , DHA significantly increased lipolysis and ATGL gene and protein expression but reduced the gene expression of three proteins related to LD formation ( Perilipin A , Caveolin-1 and Cidea ) , compared with other n-3PUFA .
Furthermore , DHA significantly increased lipolysis and ATGL gene and protein expression but reduced the gene expression of three proteins related to LD formation ( Perilipin A , Caveolin-1 and Cidea ) , compared with other n-3PUFA .
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