Comparative action of cyproterone and cyproterone acetate on pituitary and plasma gonadotropin levels, the male genital tract and spermatogenesis in the growing rat

@inproceedings{ViguierMartinez1977ComparativeAO,
  title={Comparative action of cyproterone and cyproterone acetate on pituitary and plasma gonadotropin levels, the male genital tract and spermatogenesis in the growing rat},
  author={M. C. Viguier-Martinez and Marie-Th{\'e}r{\`e}se Hochereau-de Reviers},
  year={1977}
}
In growing male rats, chronic treatment for 28 days with two anti-androgens, cyproterone and cyproterone acetate, affected the weight of testis and accessory sex organs, and induced modifications in spermatogenesis and gonadotropin functions. Antiandrogenic properties of cyproterone acetate explain the large regression in genital tract weight, and might be related to the increase in the total number of type A spermatogonia/ testis. Gestagenic properties of cyproterone acetate which inhibit this… CONTINUE READING

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