Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A

@inproceedings{Luan2017ComparativeTP,
  title={Comparative Transcriptome Profiles of Human Blood in Response to the Toll-like Receptor 4 Ligands Lipopolysaccharide and Monophosphoryl Lipid A},
  author={Liming Luan and Naeem K. Patil and Yin Guo and Antonio J. S{\'a}nchez Hern{\'a}ndez and Julia K Bohannon and Benjamin A Fensterheim and Jingbin Wang and Yaomin Xu and Perenlei Enkhbaatar and Ryan J. Stark and Edward R Sherwood},
  booktitle={Scientific reports},
  year={2017}
}
Monophosphoryl lipid A (MPLA), a less toxic derivative of lipopolysaccharide (LPS), is employed as a vaccine adjuvant and is under investigation as a non-specific immunomodulator. However, the differential response of human leukocytes to MPLA and LPS has not been well characterized. The goal of this study was to compare the differential transcriptomic… CONTINUE READING
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