• DOI:10.1161/CIRCOUTCOMES.111.000071
Corpus ID: 18340552

Comparative Tolerability and Harms of Individual Statins: A Study-Level Network Meta-Analysis of 246 955 Participants From 135 Randomized, Controlled Trials

@article{Naci2013ComparativeTA,
  title={Comparative Tolerability and Harms of Individual Statins: A Study-Level Network Meta-Analysis of 246 955 Participants From 135 Randomized, Controlled Trials},
  author={Huseyin Naci and Jasper Jan Brugts and Tony Ades},
  journal={Circulation: Cardiovascular Quality and Outcomes},
  year={2013},
  volume={6},
  pages={390–399}
}

Huseyin Naci, Jasper Jan Brugts, Tony Ades

Published 2013

Medicine

Circulation: Cardiovascular Quality and Outcomes

Background—Our objective was to estimate the comparative harms of individual statins using both placebo-controlled and active-comparator trials. Methods and Results—We systematically reviewed randomized trials evaluating different statins in participants with and without cardiovascular disease. We performed random-effects pairwise and network meta-analyses to quantify the relative harms of individual statins. We included 55 two-armed placebo-controlled and 80 two- or multiarmed active… CONTINUE READING

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