Comparative Study of Selenium and Zinc Antioxidant in HIV Sero Positive Individuals

@article{Kalio2014ComparativeSO,
  title={Comparative Study of Selenium and Zinc Antioxidant in HIV Sero Positive Individuals},
  author={Ibiene Sarah Kalio},
  journal={IOSR Journal of Pharmacy and Biological Sciences},
  year={2014},
  volume={9},
  pages={47-50}
}
Antioxidant like Selenium and Zinc trace elements are usually reduced in HIV/AIDS patients but the difference in deficiency between the two trace element is not known. This study was carried out to determine Selenium and Zinc trace element in HIV positive individuals. Serum Selenium, Zinc, albumin and total protein concentration of twenty five HIV positive individuals were compared with twenty five HIV negative individuals. Atomic absorption spectrophotometric method was used to determine… 

Tables from this paper

Nigeria and the Selenium Micronutrient: A Review

Studies in which the physiological effects of selenium supplementations were investigated revealed an improvement in CD4 counts in HIV positive human subjects, reduction in rats’ susceptibility to trypanosomiasis, improvement in reproductive function, acceleration of ulcer healing in animal model of experimental gastric ulcer and mitigation of the adverse effects inAnimal model of gastric Ulcer.

Quantitative Analysis of Selenium in Staple Foodstuffs from Kanam Local Government Area, North-Central Nigeria

Background: Although selenium was, for decades, considered toxic, many animal diseases has been found to respond to selenium. Selenium is, therefore, an essential trace element. Selenium is essential

References

SHOWING 1-10 OF 38 REFERENCES

Nutritional status and serum zinc and selenium levels in Iranian HIV infected individuals

Malnutrition found to be prevalent in Iranian human immunodeficiency virus infected individuals and low serum zinc and selenium levels are common in this population.

Relationship of trace element, immunological markers, and HIV1 infection progression

The results confirm the prevalence of abnormalities in Se and Zn levels and their relationships with nonspecific markers of immune system activity in more advanced HIV disease and appear to reflect the disease activity/progression and subsequently the immune dysregulation.

Oxidative stress and plasma antioxidant micronutrients in humans with HIV infection.

Results showed an increase in oxidative stress and a weakened antioxidant defense system in HIV-positive patients and whether supplementation of antioxidant vitamins will reduce this oxidative stress is still unknown.

Selenium deficiency in the acquired immunodeficiency syndrome.

It is concluded that selenium deficiency is a common component of the malnutrition seen in AIDS patients and aggressive nutritional support, including attention to seenium status, should be considered an integral part of the therapy of AIDS patients.

Effects of acute illness on selenium homeostasis

It is concluded that decreased plasma Se concentrations are common in ICU patients and that catabolic states are associated with increased Se losses, and the findings suggest there may be significant changes in the distribution of body Se during critical illness.

High risk of HIV-related mortality is associated with selenium deficiency.

  • M. BaumG. Shor‐Posner J. Page
  • Medicine, Biology
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
  • 1997
Results indicate that selenium deficiency is an independent predictor of survival for those with HIV-1 infection.

Nutritional status in patients with HIV infection and AIDS

HIV+ and AIDS patients showed changes in biochemical parameters, particularly an increase in fibrinogen and a trend to decreased transthyretin levels, stressing the importance of the inclusion of functional biochemical parameters in the periodic evaluation of these patients.

Influence of age and health on immune functions and trace elements.

The results indicate that only plasma copper levels were affected by age, whereas subclinical alterations in hematological or biochemical values appear to impair immune responses in the elderly.

The importance of selenium to human health