Comparative Structure Analysis of Vertebrate U17 Small Nucleolar RNA (snoRNA)

@article{Cervelli2001ComparativeSA,
  title={Comparative Structure Analysis of Vertebrate U17 Small Nucleolar RNA (snoRNA)},
  author={Manuela Cervelli and Francesco Cecconi and Marcello Giorgi and Flavia Annesi and Marco Oliverio and Paolo Mariottini},
  journal={Journal of Molecular Evolution},
  year={2001},
  volume={54},
  pages={166-179}
}
Intron-encoded U17 RNA is a member of the H/ACA box class of small nucleolar RNAs (snoRNAs) involved in ribosomal RNA (rRNA) maturation. U17 snoRNA shows typical characteristics of guide RNAs, which specify sites of pseudouridylation on the precursor rRNA (pre-rRNA). However, in spite of the presence of H and ACA boxes and short regions complementary to the pre-rRNA, its secondary structure does not show any evident pseudouridylation pocket. Moreover, its length is larger than the typical one… Expand
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