Comparative Proteomic Analysis of Aminoglycosides Resistant and Susceptible Mycobacterium tuberculosis Clinical Isolates for Exploring Potential Drug Targets

@inproceedings{Sharma2015ComparativePA,
  title={Comparative Proteomic Analysis of Aminoglycosides Resistant and Susceptible Mycobacterium tuberculosis Clinical Isolates for Exploring Potential Drug Targets},
  author={Divakar Sharma and Bhavnesh Kumar and Manju Lata and Beenu Joshi and Krishnamurthy Venkatesan and Sangeeta Shukla and Deepa Bisht and Deepak Kaushal},
  booktitle={PloS one},
  year={2015}
}
Aminoglycosides, amikacin (AK) and kanamycin (KM) are second line anti-tuberculosis drugs used to treat tuberculosis (TB) and resistance to them affects the treatment. Membrane and membrane associated proteins have an anticipated role in biological processes and pathogenesis and are potential targets for the development of new diagnostics/vaccine/therapeutics. In this study we compared membrane and membrane associated proteins of AK and KM resistant and susceptible Mycobacterium tuberculosis… CONTINUE READING
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