Comparative Neuroprotective Effects of Dexamethasone and Minocycline during Hepatic Encephalopathy

  title={Comparative Neuroprotective Effects of Dexamethasone and Minocycline during Hepatic Encephalopathy},
  author={Maha Mohamed Gamal and Zainab Abdel Wahab and Mohamed A Eshra and Laila Ahmed Rashed and Nivin Sharawy},
  booktitle={Neurology research international},
Objective. Encephalopathy and brain edema are serious complications of acute liver injury and may lead to rapid death of patients. The present study was designed to investigate the role of the inflammatory mediators and oxidative stress in the cytotoxic brain oedema and the neuroprotective effects of both minocycline and dexamethasone. Methods. 48 male albino rats were divided into 4 groups: control group, acute liver injury (ALI) group, minocycline pretreated ALI group, and dexamethasone… CONTINUE READING
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