Comparative Methods for Reconstructing Ancient Genome Organization.

@article{Anselmetti2018ComparativeMF,
  title={Comparative Methods for Reconstructing Ancient Genome Organization.},
  author={Yoann Anselmetti and Nina Luhmann and S{\`e}verine B{\'e}rard and Eric Tannier and C{\'e}dric Chauve},
  journal={Methods in molecular biology},
  year={2018},
  volume={1704},
  pages={
          343-362
        }
}
Comparative genomics considers the detection of similarities and differences between extant genomes, and, based on more or less formalized hypotheses regarding the involved evolutionary processes, inferring ancestral states explaining the similarities and an evolutionary history explaining the differences. In this chapter, we focus on the reconstruction of the organization of ancient genomes into chromosomes. We review different methodological approaches and software, applied to a wide range of… CONTINUE READING
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