Comparative Kinetics and Response to the Benzodiazepine Agonists Triazolam and Zolpidem : Evaluation of Sex-Dependent Differences 1

Abstract

Eighteen healthy volunteers (10 men and 8 women) participated in a single-dose, double-blind, three-way crossover pharmacokinetic and pharmacodynamic study. Treatment conditions were 0.25 mg of triazolam, a full-agonist benzodiazepine ligand; 10 mg of zolpidem, an imidazopyridine having relative selectivity for the type 1 benzodiazepine receptor subtype… (More)

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