Comparative Immunohistochemical Study of Multicystic Dysplastic Kidneys With and Without Obstruction

@inproceedings{Rojas2011ComparativeIS,
  title={Comparative Immunohistochemical Study of Multicystic Dysplastic Kidneys With and Without Obstruction},
  author={Claudia P Rojas and Arnel K Urbiztondo and Jocelyn H. Bruce and Maria Matilde Rodriguez},
  booktitle={Fetal and pediatric pathology},
  year={2011}
}
Etiology of multicystic dysplastic kidney (MCDK) remains unknown. Not all cases are associated with obstruction. We compared by immunohistochemistry 17 cases of MCDK (10 cases with and seven without obstruction) to 17 controls and 20 fetal kidneys. TGF-β was negative in obstructive MCDKs and positive in nonobstructive MCDK. IGF2 was overexpressed in… CONTINUE READING