Comparative Genomics Reveals the Origins and Diversity of Arthropod Immune Systems

  title={Comparative Genomics Reveals the Origins and Diversity of Arthropod Immune Systems},
  author={William J. Palmer and Francis M. Jiggins},
  booktitle={Molecular biology and evolution},
Insects are an important model for the study of innate immune systems, but remarkably little is known about the immune system of other arthropod groups despite their importance as disease vectors, pests, and components of biological diversity. Using comparative genomics, we have characterized the immune system of all the major groups of arthropods beyond insects for the first time--studying five chelicerates, a myriapod, and a crustacean. We found clear traces of an ancient origin of innate… CONTINUE READING
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