Comparative Genomic Hybridization As a New Method for Detection of Genomic Imbalance


Comparative Genomic Hybridization (CGH) is a molecular cytogenetic method for detecting chromosomal imbalances by comparing the copy number of DNA sequences in cells of tested tissue and the reference specimen. CGH is based on two-color fluorescence suppressive in situ hybridization of genomic test and reference DNAs, each labeled with a different… (More)
DOI: 10.1023/A:1014342607507