Comparative Genome Sequencing for Discovery of Novel Polymorphisms in Bacillus anthracis

  title={Comparative Genome Sequencing for Discovery of Novel Polymorphisms in Bacillus anthracis},
  author={Timothy D. Read and Steven L. Salzberg and Mihai Pop and Martin Shumway and Lowell A. Umayam and Lingxia Jiang and Erik K. Holtzapple and Joseph D. Busch and Kimothy L Smith and James M. Schupp and Daniel Solomon and Paul S Keim and Claire M. Fraser},
  pages={2028 - 2033}
Comparison of the whole-genome sequence ofBacillus anthracis isolated from a victim of a recent bioterrorist anthrax attack with a reference reveals 60 new markers that include single nucleotide polymorphisms (SNPs), inserted or deleted sequences, and tandem repeats. Genome comparison detected four high-quality SNPs between the two sequenced B. anthracischromosomes and seven differences among different preparations of the reference genome. These markers have been tested on a collection of… 

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