Comparative Genome Sequencing for Discovery of Novel Polymorphisms in Bacillus anthracis

@article{Read2002ComparativeGS,
  title={Comparative Genome Sequencing for Discovery of Novel Polymorphisms in Bacillus anthracis},
  author={T. Read and S. Salzberg and M. Pop and M. Shumway and L. Umayam and L. Jiang and E. Holtzapple and J. Busch and K. Smith and J. Schupp and Daniel Solomon and P. Keim and C. Fraser},
  journal={Science},
  year={2002},
  volume={296},
  pages={2028 - 2033}
}
Comparison of the whole-genome sequence ofBacillus anthracis isolated from a victim of a recent bioterrorist anthrax attack with a reference reveals 60 new markers that include single nucleotide polymorphisms (SNPs), inserted or deleted sequences, and tandem repeats. Genome comparison detected four high-quality SNPs between the two sequenced B. anthracischromosomes and seven differences among different preparations of the reference genome. These markers have been tested on a collection of… Expand
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