Comparative Efficacy of Yohimbine Against Pyridostigmine for the Treatment of Orthostatic Hypotension in Autonomic Failure

@article{Shibao2010ComparativeEO,
  title={Comparative Efficacy of Yohimbine Against Pyridostigmine for the Treatment of Orthostatic Hypotension in Autonomic Failure},
  author={C. Shibao and L. Okamoto and A. Gamboa and C. Yu and A. Diedrich and S. Raj and D. Robertson and I. Biaggioni},
  journal={Hypertension},
  year={2010},
  volume={56},
  pages={847-851}
}
  • C. Shibao, L. Okamoto, +5 authors I. Biaggioni
  • Published 2010
  • Medicine
  • Hypertension
  • Orthostatic hypotension affects patients with autonomic failure producing considerable disability because of presyncopal symptoms. Severely affected patients may have residual sympathetic tone that can be engaged to increase blood pressure (BP) with the &agr;-2 adrenergic antagonist yohimbine. This medication activates sympathetic outflow centrally and unrestrains norepinephrine release from noradrenergic neurons. Alternatively, the acetylcholinesterase inhibitor, pyridostigmine, can increase… CONTINUE READING
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    References

    SHOWING 1-10 OF 31 REFERENCES
    Pyridostigmine treatment trial in neurogenic orthostatic hypotension.
    • 209
    • PDF
    Treatment of orthostatic hypotension.
    • 79
    Neuropharmacologic Distinction of Neurogenic Orthostatic Hypotension Syndromes
    • 29