Comparative Effects of Volume Loading on Pulmonary Venous Flow in Dogs with Normal Heart and with Myocardial Ischemia

@article{Akita1997ComparativeEO,
  title={Comparative Effects of Volume Loading on Pulmonary Venous Flow in Dogs with Normal Heart and with Myocardial Ischemia},
  author={Sachie Akita and Nobuyuki Ohte and Takeshi Hashimoto and Hitomi Narita and Kenji Kobayashi and Takao Fujinami},
  journal={Angiology},
  year={1997},
  volume={48},
  pages={401 - 411}
}
The influences of cardiac loading conditions and left ventricular performance on pulmonary venous flow are poorly understood. The authors studied the effects of volume loading on the pattern of pulmonary venous flow in normal and ischemic hearts. Thirteen anesthetized dogs were equipped with a transit-time ultrasonic flow probe around the left upper pulmonary vein. In 6 of the dogs, the left anterior descending artery was ligated to induce myocardial ischemia. The remaining 7 dogs had normal… 

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References

SHOWING 1-10 OF 36 REFERENCES

Pericardial Modulation of Right and Left Ventricular Diastolic Interaction

The pericardium has a small but significant effect on LV diastolic P-V relations at physiological RV filling pressures, and this effect becomes considerable at high RV filling pressure.

Pulmonary venous flow velocity: relation to hemodynamics, mitral flow velocity and left atrial volume, and ejection fraction.

Blood flow in pulmonary veins: III. Simultaneous measurements of their dimensions, intravascular pressure and flow.

The extraparenchymal pulmonary veins act as a reservoir to the left atrium so that left ventricular stroke volume can be maintained relatively unaffected by beat by beat changes in right ventricular strokes, which could otherwise impede venous outflow of blood from the lung capillary bed.

Pulmonary venous flow pattern--its relationship to cardiac dynamics. A pulsed Doppler echocardiographic study.

It is suggested that pulmonary venous flow is influenced by dynamic changes in left atrial pressure created by contraction and relaxation of the atrium and ventricle, which is consistent with data obtained from invasive measurements in both dogs and man.

Importance of Left Atrial Function in Patients with Myocardial Infarction

The left atrial contribution to left ventricular function is increased in patients with remote myocardial infarction, attributed to the Frank- Starling mechanism in the left atrium.

Relation of pulmonary vein to mitral flow velocities by transesophageal Doppler echocardiography. Effect of different loading conditions.

This study relates changes in pulmonary venous and mitral flow velocities during different loading conditions as assessed by transesophageal echocardiography in the operating room to indicate that diastolic flow velocity in the pulmonary vein is determined by the same factors that influence theMitral flow velocity curves.

Left ventricular filling dynamics: influence of left ventricular relaxation and left atrial pressure.

PRFR is determined by both the left atrial pressure and the left ventricular relaxation rate and should be used with caution as an index ofleft ventricular diastolic function.

Blood flow in pulmonary veins: II. The influence of events transmitted from the right and left sides of the heart.

It is postulated that the thin walled extraperenchymal pulmonary veins together behave as a collapsible reservoir which enables outflow from them to be determined by changes in left atrial pressure, in spite of variations of pulsatile flow into them from the lungs.

Study on left atrial contractile performance--participation of Frank-Starling mechanism.

It is shown that an increase in the "preload" of theleft atrium augmented the stroke volume of the left atrium, which means that Frank-Starling mechanism is operative in the leftAtrium.