Comparative CD4 T-cell responses of reverse transcriptase inhibitor therapy with or without nelfinavir matched for viral exposure.

@article{Kravcik2001ComparativeCT,
  title={Comparative CD4 T-cell responses of reverse transcriptase inhibitor therapy with or without nelfinavir matched for viral exposure.},
  author={Stephen Kravcik and Allan Magill and Bejal Sanghvi and Robert Ogden and William D. Cameron and Ronald L. Lewis and Gang Yu and Andrew D Badley},
  journal={HIV clinical trials},
  year={2001},
  volume={2 2},
  pages={160-70}
}
BACKGROUND Therapy of HIV infection with protease inhibitors (PIs) may be associated with improvements in CD4 T-cell number via a mechanism that is independent of effects on plasma viral load (VL). PURPOSE To compare CD4 responses of patients who receive reverse transcriptase inhibitor (RTI) therapies with or without a PI, matched for viral exposure. METHODS Patient data were analyzed from two prospective randomized trials of antiviral therapy with or without nelfinavir. Total viral… CONTINUE READING