Comparative Antithrombotic Effects of Magnesium Sulfate and the Platelet Glycoprotein IIb/IIIa Inhibitors Tirofiban and Eptifibatide in a Canine Model of Stent Thrombosis

@article{Rukshin2002ComparativeAE,
  title={Comparative Antithrombotic Effects of Magnesium Sulfate and the Platelet Glycoprotein IIb/IIIa Inhibitors Tirofiban and Eptifibatide in a Canine Model of Stent Thrombosis},
  author={Vladimir Rukshin and P. Shah and B. Cercek and A. Finkelstein and V. Tsang and S. Kaul},
  journal={Circulation: Journal of the American Heart Association},
  year={2002},
  volume={105},
  pages={1970-1975}
}
Background—Antithrombotic effects of glycoprotein IIb/IIIa inhibitors and magnesium are known, but their comparative effects on stent thrombosis are not known. Our objective was to compare the antithrombotic effects of the glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide with magnesium in an ex vivo canine arteriovenous shunt model of stent thrombosis. Methods and Results—Control nitinol stents were expanded to 2 mm in diameter in a tubular perfusion chamber interposed in the shunt… Expand
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Magnesium and cardiovascular system.
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