Comparative Antihypertensive Effects of Guanabenz and Clonidine

@article{Walker1982ComparativeAE,
  title={Comparative Antihypertensive Effects of Guanabenz and Clonidine},
  author={Barry R. Walker and Larry E. Hare and M W Deitch},
  journal={Journal of International Medical Research},
  year={1982},
  volume={10},
  pages={14 - 6}
}
The safety and efficacy of guanabenz and clonidine were compared in 188 hypertensive patients during a 6-month double-blind trial. Mean supine diastolic blood pressure (SDBP) decreased from 103 to 88 mm Hg (p < 0.01) among guanabenz patients and from 101 to 88 mm Hg (p < 0.01) among clonidine patients who completed 6 months of b.i.d. therapy. Clinically significant individual SDBP decreases occurred in 85% of the guanabenz patients and in 83% of the clonidine patients after 6 months. Adverse… 
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