Comparative Anti-Platelet Profiling Reveals a Potent Anti-Aggregatory Effect of CD34+ Progenitor Cell-Derived Late-Outgrowth Endothelial Cells in vitro.

@article{Chantzichristos2018ComparativeAP,
  title={Comparative Anti-Platelet Profiling Reveals a Potent Anti-Aggregatory Effect of CD34+ Progenitor Cell-Derived Late-Outgrowth Endothelial Cells in vitro.},
  author={Vasileios G Chantzichristos and Fani Gkrozou and Konstantinos Stellos and Minas Paschopoulos and Alexandros D. Tselepis},
  journal={Journal of vascular research},
  year={2018},
  volume={55 1},
  pages={
          13-25
        }
}
BACKGROUND/AIMS Platelets affect endothelial progenitor cell (EPC) functionality, inducing their differentiation into mature endothelial cells. However, it remains to be established whether EPCs can influence platelet functionality. METHODS Mononuclear proangiogenic cells (MPCs) and early outgrowth cells (EOCs) were prepared from peripheral blood mononuclear cells, whereas late-outgrowth endothelial cells (OECs) were prepared from cord blood CD34+ cells. The effect of the above cells and… CONTINUE READING