Comparative Analysis of Predictive Biomarkers for Therapeutical Strategies in Colorectal Cancer

  title={Comparative Analysis of Predictive Biomarkers for Therapeutical Strategies in Colorectal Cancer},
  author={M. Gasser and C. Gerstlauer and M. Grimm and M. Bueter and T. Lebedeva and J. Lutz and U. Maeder and C. Ribas and E. Nichiporuk and A. Thalheimer and U. Heemann and A. Thiede and D. Meyer and A. Waaga-Gasser},
  journal={Annals of Surgical Oncology},
  • M. Gasser, C. Gerstlauer, +12 authors A. Waaga-Gasser
  • Published 2006
  • Medicine
  • Annals of Surgical Oncology
  • BackgroundPrognostic information regarding the risk of postoperative tumor recurrence defined by a profile of serological, morphological and/or molecular markers can have potential value, particularly for patients with colorectal carcinoma (CRC) of the International Union Against Cancer (UICC) stage II/III who may benefit from adjuvant chemotherapy after surgery.MethodsA retrospective study of 783 patients with CRC (UICC I–III) including a subgroup analysis of 116 subjects was conducted to… CONTINUE READING
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