Comparative, quantitative study of lymphoid and non-lymphoid uptake of 60 nm polystyrene particles.

Uptake by gut epithelial tissue of 60 nm polystyrene particles was studied in female Sprague-Dawley rats (180 g, 9 weeks old) after 5 days oral dosing by gavage (14 mg/kg). The gut was divided into lymphoid and non-lymphoid tissue of the small and large intestine, prior to analysis for polystyrene by gel permeation chromatography (GPC). Approximately 10% of… CONTINUE READING