Comparable efficacy with similarly low risk of hypoglycaemia in patient- vs physician-managed basal insulin initiation and titration in insulin-naïve type 2 diabetic subjects: the Italian Titration Approach Study (ITAS).

@article{Bonadonna2020ComparableEW,
  title={Comparable efficacy with similarly low risk of hypoglycaemia in patient- vs physician-managed basal insulin initiation and titration in insulin-na{\"i}ve type 2 diabetic subjects: the Italian Titration Approach Study (ITAS).},
  author={R C Bonadonna and Andrea Giaccari and Raffaella Buzzetti and Gianluca Perseghin and Domenica Cucinotta and Angelo Avogaro and Gianluca Aimaretti and Maddalena Larosa and C G Fanelli and Geremia B. Bolli},
  journal={Diabetes/metabolism research and reviews},
  year={2020},
  pages={
          e3304
        }
}
  • R C Bonadonna, Andrea Giaccari, +7 authors Geremia B. Bolli
  • Published in
    Diabetes/metabolism research…
    2020
  • Medicine
  • AIMS People with uncontrolled type 2 diabetes (T2DM) often delay initiating and titrating basal insulin. Patient-managed titration may reduce such deferral. The Italian Titration Approach Study (ITAS) compared the efficacy and safety of insulin glargine 300 U/mL (Gla-300) initiation and titration using patient- (nurse-supported) or physician-management in insulin-naïve patients with uncontrolled T2DM. MATERIALS AND METHODS ITAS was a multicentre, phase IV, 24-week, open-label, randomized (1:1… CONTINUE READING

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