Comparable effects of Jiedu Granule, a compound Chinese herbal medicine, and sorafenib for advanced hepatocellular carcinoma: A prospective multicenter cohort study.

  title={Comparable effects of Jiedu Granule, a compound Chinese herbal medicine, and sorafenib for advanced hepatocellular carcinoma: A prospective multicenter cohort study.},
  author={Hetong Zhao and Y. Meng and X. Zhai and Bin-Bin Cheng and Shasha Yu and M. Yao and Hui-Xia Yin and X. Wan and Yun-ke Yang and H. Liu and F. Shen and C. Ling},
  journal={Journal of integrative medicine},
OBJECTIVE Sorafenib has been extensively used for the treatment of advanced hepatocellular carcinoma (HCC), and Chinese herbal medicine has also been used to manage advanced HCC. The present work evaluates the effectiveness and safety of Jiedu (JD) Granule, a compound of traditional Chinese herbal medicine, side-by-side with sorafenib for the treatment of advance HCC. METHODS Patients with advanced HCC receiving treatment with JD Granule or sorafenib were enrolled from December 2014 to March… Expand
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Traditional insect Chinese medicine and related preparations could be recommended as auxiliary therapy combined chemotherapy for HCC therapy and show significantly effectiveness and safety in objective response rate. Expand
Effects of adjuvant traditional Chinese medicine therapy on long-term survival in patients with hepatocellular carcinoma.
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Jie-du granule preparation for the treatment of advanced hepatocellular carcinoma: a retrospective cohort study of 177 patients
Jie-du granule preparation may prolong survival of patients with advanced HCC and for patients with two or fewer of these independent risk factors, the overall median survival of those treated with JD was significantly longer than that of patients receiving BST. Expand
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Sorafenib in advanced hepatocellular carcinoma.
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Jiedu Granules plus Cinobufacini Injection, a combination that is commonly used for post-operation management of HCC, can postpone tumor recurrence and metastasis, prolong the survival time and increase the survival rate of post-surgical patients with HCC. Expand
Traditional herbal medicine prevents postoperative recurrence of small hepatocellular carcinoma: A randomized controlled study
The results indicated that THM prevented the recurrence of SHCC with an efficacy that was superior to that of transarterial chemoembolization (TACE) during a median follow-up of 26.61 months. Expand