Compacting the heart with Notch

Abstract

nature medicine volume 19 | number 2 | FebruArY 2013 133 BCL-2 than on other antiapoptotic proteins and that the high affinity of ABT-199 for this antiapoptotic protein accounts for its activity. Time will tell whether resistance to ABT-199 emerges and, if so, whether it can be associated with BCL-XL expression. Indeed, cells that ectopically express BCL-XL… (More)
DOI: 10.1038/nm.3071

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