Compact archaeal variant of heme A synthase.

  title={Compact archaeal variant of heme A synthase.},
  author={Anna Lewin and Lars Hederstedt},
  journal={FEBS letters},
  volume={580 22},
The N- and C-terminal halves of the heme A synthase polypeptide of Bacillus subtilis, and many other organisms, are homologous. This indicates that these enzyme proteins originate from a tandem duplication and fusion event of a gene encoding a protein half as large. The ape1694 gene of the hyperthermophilic archaeon Aeropyrum pernix encodes a protein that is similar to the hypothetical small primordial protein. We demonstrate that this A. pernix protein is a heat-stable membrane bound heme A… CONTINUE READING

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