Comorbidity of anxiety and unipolar mood disorders.

  title={Comorbidity of anxiety and unipolar mood disorders.},
  author={Susan Mineka and David Watson and Lee Anna Clark},
  journal={Annual review of psychology},
Research on relationships between anxiety and depression has proceeded at a rapid pace since the 1980s. The similarities and differences between these two conditions, as well as many of the important features of the comorbidity of these disorders, are well understood. The genotypic structure of anxiety and depression is also fairly well documented. Generalized anxiety and major depression share a common genetic diathesis, but the anxiety disorders themselves are genetically hetergeneous… 

Anxiety Disorders and Depression Comorbidity

The chapter reviews cross-sectional and longitudinal epidemiological studies related to the cooccurrence of anxiety disorders and depression. Results suggest that anxiety disorders and depression

The overlap between anxiety, depression, and obsessive-compulsive disorder

  • G. Goodwin
  • Psychology
    Dialogues in clinical neuroscience
  • 2015
Evidence of shared genes is still based mainly on twin studies, but the shared neurobiology can be investigated directly by the investigation of emotional or cognitive bias either behaviorally or using functional brain imaging.

Differentiating the mood and anxiety disorders: a quadripartite model.

  • D. Watson
  • Psychology
    Annual review of clinical psychology
  • 2009
It is demonstrated that two quantitative elements need to be considered when analyzing the properties of symptoms-the level of specificity and the magnitude of the general distress variance and that these quantitative elements can be used to organize relevant symptoms into four groups that reflect varying combinations of distress and specificity.

Hierarchical structures of affect and psychopathology and their implications for the classification of emotional disorders

The existing structural evidence establishes that the mood and anxiety disorders should be collapsed together into an overarching superclass of emotional disorders, which can be decomposed into three subclasses: the distress disorders, the fear disorders, and the bipolar disorders.

Antidepressants and brain monoaminergic systems: a dimensional approach to understanding their behavioural effects in depression and anxiety disorders.

How chronic antidepressant treatment might regulate the tonic activity and/or phasic reactivity of brain monoaminergic systems to account for their ability to effectively modify the behavioural dimensions underlying improvement in both depression and anxiety disorders is discussed.

Positive and Negative Affective Dysfunction in Psychopathology

Moods are a constant feature of human experience. Although we all experience good and bad moods, there are individual differences in the propensity to experience positive and negative feeling states.

Neuroticism as a common feature of the depressive and anxiety disorders: a test of the revised integrative hierarchical model in a national sample.

The revised integrative hierarchical model of depression and anxiety supported the model insofar as high neuroticism was shared across the depressive and anxiety disorders and was particularly elevated in people with comorbid depression and Anxiety.

Understanding the Latent Structure of the Emotional Disorders in Children and Adolescents

The prevailing view that the co-occurrence of anxiety and mood disorders in children is in part due to a common vulnerability is supported, as depression and generalized anxiety loaded more highly onto the higher-order factor than the other disorders.

Differential affect structure in depressive and anxiety disorders

A dynamic model of affect suggests that positive and negative affect (PA and NA) are normally relatively independent of one another, whereas the heightened apprehensiveness and narrowed cognitive



Comorbidity among anxiety disorders: implications for treatment and DSM-IV.

Treatment implications are presented with preliminary data on the effects of psychosocial treatment of panic disorder on co-morbid generalized anxiety disorder and implications of comorbidity for research on the nature of psychopathology and the ultimate integration of dimensional and categorical features in the nosology are considered.

Comorbidity among anxiety disorders: implications for treatment and DSM-IV

Research on comorbidity among psychological disorders is relatively new. Yet, comorbidity data have fundamental significance for classification and treatment. This significance is particularly

Childhood anxiety disorders and depression: Phenomenology, comorbidity, and intervention issues

Abstract Although burgeoning literatures have developed on childhood anxiety disorders and depression, little attention has been given to the association between these disorders. We examine the

Positive and negative affectivity and their relation to anxiety and depressive disorders.

Findings in normal samples suggest that assessment of two broad mood factors—Negative Aflect (NA) and Positive Affect (PA) may improve their differentiation, and the results suggest that strengthening the PA component in depression measures may enhance their discriminative power.

Depressive disorders in childhood. IV. A longitudinal study of comorbidity with and risk for anxiety disorders.

Conurrent maternal psychopathology and poor physical health increased the risk of anxiety disorder in the children, but a history of prior separation from parental figures did not seem to have an effect.

The comorbidity of anxiety disorders with personality, depressive, alcohol and drug disorders

Anxiety disorders seldom exist in isolation from personality traits and disorders, from depressive symptomatology, and from alcohol and drug use and abuse. This review examines the relationships

Evidence Against a Genetic Relationship between Tourette's Syndrome and Anxiety, Depression, Panic and Phobic Disorders

No other psychiatric disorder was significantly elevated among the relatives who did not have TS, CT or OCD when compared with a control sample, which is not consistent with the hypothesis that a wide range of psychiatric and behavioural disorders are variant expressions of TS.

Self-report differentiation of anxiety and depression in an anxiety disorders sample.

There is a prevalent belief that self-reports of anxiety and depression are often indistinguishable, based largely on findings with college students or mixed psychiatric samples. This study focused

Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications.

Results suggest that anxiety and depression can be reliably and validly assessed; moreover, although these disorders share a substantial component of general affective distress, they can be differentiated on the basis of factors specific to each syndrome.

Comorbidity of personality disorders and depression: implications for treatment.

The findings support the common belief that personality disorders are associated with a poorer response to treatment for depression and suggest that the presence of depression may be a positive prognostic indicator for patients with borderline and antisocial personality disorder.