Comorbidity: A network perspective

  title={Comorbidity: A network perspective},
  author={Ang{\'e}lique O. J. Cramer and Lourens J. Waldorp and H.L.J. van der Maas and Denny Borsboom},
  journal={Behavioral and Brain Sciences},
  pages={137 - 150}
Abstract The pivotal problem of comorbidity research lies in the psychometric foundation it rests on, that is, latent variable theory, in which a mental disorder is viewed as a latent variable that causes a constellation of symptoms. From this perspective, comorbidity is a (bi)directional relationship between multiple latent variables. We argue that such a latent variable perspective encounters serious problems in the study of comorbidity, and offer a radically different conceptualization in… 

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