Comorbid chronic diseases, discordant impact on mortality in older people: a 14-year longitudinal population study

@article{Caughey2009ComorbidCD,
  title={Comorbid chronic diseases, discordant impact on mortality in older people: a 14-year longitudinal population study},
  author={Gillian E. Caughey and Emmae N. Ramsay and Agnes Vitry and Andrew L. Gilbert and Mary A. Luszcz and Philip Ryan and Elizabeth Ellen Roughead},
  journal={Journal of Epidemiology \& Community Health},
  year={2009},
  volume={64},
  pages={1036 - 1042}
}
Objectives To determine the impact of comorbid chronic diseases on mortality in older people. Design Prospective cohort study (1992–2006). Associations between numbers of chronic diseases or mutually exclusive comorbid chronic diseases on mortality over 14 years, by Cox proportional hazards model adjusting for sociodemographic variables or Kaplan–Meier analyses, respectively. Setting Population based, Australia. Participants 2087 randomly selected participants aged ≥65 years old, living in the… Expand
The effect of comorbidities on survival in persons with Alzheimer’s disease: a matched cohort study
TLDR
Alzheimer’s disease is the major factor affecting survival, but comorbidities further decrease survival also in individuals with Alzheimer's disease, therefore, appropriate management of care of these comorbbidities might affect not only survival but also the wellbeing of this vulnerable population. Expand
Chronic conditions and multimorbidity in population aged 90 years and over: associations with mortality and long-term care admission.
BACKGROUND prevalence of many chronic conditions is rising in the aging population worldwide. However, the long-term impact of these conditions and multimorbidity on other health outcomes in very oldExpand
Gender Differences between Multimorbidity and All-Cause Mortality among Older Adults
TLDR
It is found that all-cause mortality increased as diseases are added to an individual and women and men presented different mortality patterns according to multimorbidity. Expand
The Combined Effect of Cancer and Cardiometabolic Conditions on the Mortality Burden in Older Adults
TLDR
Combinations of cancer and cardiometabolic conditions accelerate mortality rates in older adults differently, and most studies investigating mortality associated with multimorbidity used disease counts, which provide little guidance for managing complex patients as they age. Expand
Prevalence and incidence density rates of chronic comorbidity in type 2 diabetes patients: an exploratory cohort study
TLDR
High prevalence and incidence density rates for both concordant and discordant comorbidity are found in patients with newly diagnosed type 2 diabetes, thus future research and clinical practice should take discordant COMORbidity in patientswith T2D into account. Expand
Association between cardiometabolic disease multimorbidity and all-cause mortality in 2 million women and men registered in UK general practices
TLDR
Myocardial infarction, stroke and diabetes were associated with excess mortality, without evidence of any amplification of risk in people with all three diseases. Expand
Global health care use by patients with type-2 diabetes: Does the type of comorbidity matter?
TLDR
In patients with type-2 diabetes, the coexistence of mental comorbidity significantly increases the use of unplanned hospital services, and discordantComorbidities have an important effect on specialised care use. Expand
The impact of socioeconomic status and multimorbidity on mortality: a population-based cohort study
TLDR
It is suggested that LEL is associated with higher overall and premature mortality and that the association is affected by MM, lifestyle factors, and quality of life. Expand
Prevalence of disability according to multimorbidity and disease clustering: a population-based study
TLDR
The findings suggest specific pairs of diseases are much more highly associated with disability than others, particularly diseases coupled with dementia, which may improve prevention of disablement and planning of resource distribution. Expand
Associations between cardiovascular disease severity, osteoarthritis co-morbidity and physical health: a population-based study.
TLDR
In cardiovascular populations with differing severity, the co-morbid addition of OA was associated with incrementally poorer physical health, but such interactions were less than additive. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 44 REFERENCES
Osteoarthritis: a comorbid marker for longer life?
TLDR
The association between osteoarthritis and lower rates of mortality is notable and replicating these findings to explore causal relationships is important. Expand
Mortality Rate in Veterans with Multiple Chronic Conditions
TLDR
Patients with multiple chronic conditions have higher mortality rates, and when studying patients with multiple coexisting illnesses, it is important to understand not only that several conditions may be present but that specific conditions can differentially impact the risk of mortality. Expand
Prevalence of morbidity and multimorbidity in elderly male populations and their impact on 10-year all-cause mortality: The FINE study (Finland, Italy, Netherlands, Elderly).
TLDR
In these elderly men prevalent morbidity and comorbidity was relatively common and it explained a large proportion of excess in all-cause mortality in 10 years of follow-up. Expand
Secular decline in mortality from coronary heart disease in adults with diabetes mellitus: cohort study
TLDR
The strong general reduction in mortality rates from coronary heart disease from the first to the second follow-up period also benefited people with diabetes, but the more than twofold higher mortality from coronaryHeart disease associated with diabetes persisted over time. Expand
Mortality Risk Varies According to Gender and Change in Depressive Status in Very Old Adults
TLDR
Depression confers a greater risk of mortality for men than women with incident depression in old age representing the greatest risk for men. Expand
Effect of social networks on 10 year survival in very old Australians: the Australian longitudinal study of aging
TLDR
Survival time may be enhanced by strong social networks among older Australians, and these may be important in lengthening survival. Expand
Relationship Between Multimorbidity and Health-Related Quality of Life of Patients in Primary Care
TLDR
Physical more than mental health deteriorated with increasing multimorbidity, and perceived social support and self-perception of economic status were significantly related to all scales of the SF-36, which adversely affected HRQOL in primary-care adult patients. Expand
Prevalence and risk factors for depression in a longitudinal, population-based study including individuals in the community and residential care.
TLDR
Depression is strongly linked with factors indicating increased dependency, and risk assessment and targeting of intervention strategies to prevent depression in late life should incorporate changes in functional capacity, mental status, and need for residential care. Expand
Depression and Diabetes: A Potentially Lethal Combination
TLDR
Among a large Medicare cohort of fee-for-service beneficiaries with diabetes, comorbid depression was associated with an increase in all-cause mortality over a two-year period. Expand
The impact of comorbid chronic conditions on diabetes care.
TLDR
The increasing prevalence of multimorbidity among older diabetic adults is at least in part an unintended consequence of success in improving diabetes treatment quality and may miss opportunities to improve patients’ functioning, quality of life, and mortality risk. Expand
...
1
2
3
4
5
...