Communication between Human Dendritic Cell Subsets in Tuberculosis: Requirements for Naive CD4+ T Cell Stimulation

@inproceedings{Lozza2014CommunicationBH,
  title={Communication between Human Dendritic Cell Subsets in Tuberculosis: Requirements for Naive CD4+ T Cell Stimulation},
  author={Laura Lozza and Maura Farinacci and Marina Bechtle and Manuela St{\"a}ber and Ulrike Zedler and Andrea Baiocchini and Franca del Nonno and Stefan H. E. Kaufmann},
  booktitle={Front. Immunol.},
  year={2014}
}
Human primary dendritic cells (DCs) are heterogeneous by phenotype, function, and tissue localization and distinct from inflammatory monocyte-derived DCs. Current information regarding the susceptibility and functional role of primary human DC subsets to Mycobacterium tuberculosis (Mtb) infection is limited. Here, we dissect the response of different primary DC subsets to Mtb infection. Myeloid CD11c(+) cells and pDCs (C-type lectin 4C(+) cells) were located in human lymph nodes (LNs) of… CONTINUE READING
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