Communication: Theoretical Insights from Binding of Neigleria fowleri Cell Division Proteins with Amoebicidal Quassinoids

@article{Basharat2018CommunicationTI,
  title={Communication: Theoretical Insights from Binding of Neigleria fowleri Cell Division Proteins with Amoebicidal Quassinoids},
  author={Zarrin Basharat and Shumaila Zaib and Azra Yasmin},
  journal={bioRxiv},
  year={2018}
}
The ameboflagellate Neigleria fowleri, also known as brain eating amoeba is responsible for fatal primary amoebic meningoencephalitis (PAM) infection in humans. Cell division proteins (CDPs) in N. fowleri have been uncharacterized until now, despite their importance in the initiation of cell division and proliferation of the pathogen. Here, we report characterization and structural assembly of eight such proteins associated with division and docking them with anti-amoebic quassinoid compounds… 

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