Communicating hydrocephalus in adult rats with kaolin obstruction of the basal cisterns or the cortical subarachnoid space.

@article{Li2008CommunicatingHI,
  title={Communicating hydrocephalus in adult rats with kaolin obstruction of the basal cisterns or the cortical subarachnoid space.},
  author={Jie Li and James Pat McAllister and Yimin Shen and Mark E. Wagshul and Janet M. Miller and Michael Robert Egnor and Miles G Johnston and E. Mark Haacke and Marion L. Walker},
  journal={Experimental neurology},
  year={2008},
  volume={211 2},
  pages={351-61}
}
Communicating hydrocephalus (CH) occurs frequently, but clinically-relevant animal models amenable to diagnostic imaging and cerebrospinal fluid shunting are not available. In order to develop and characterize models of subarachnoid space (SAS) obstruction at the basal cisterns (BC) or cerebral convexities (CX), 25% kaolin was injected in adult female Sprague-Dawley rats following halothane anesthesia; intact- or saline-injected animals served as controls. For BC animals (n=28 hydrocephalics, n… CONTINUE READING

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