Common virulence factors for bacterial pathogenicity in plants and animals.

@article{Rahme1995CommonVF,
  title={Common virulence factors for bacterial pathogenicity in plants and animals.},
  author={Laurence G Rahme and E. J. Stevens E. J. Stevens and Sean F Wolfort and Jonathan Y. Shao and Ronald G. Tompkins and Frederick M. Ausubel},
  journal={Science},
  year={1995},
  volume={268 5219},
  pages={1899-902}
}
A Pseudomonas aeruginosa strain (UCBPP-PA14) is infectious both in an Arabidopsis thaliana leaf infiltration model and in a mouse full-thickness skin burn model. UCBPP-PA14 exhibits ecotype specificity for Arabidopsis, causing a range of symptoms from none to severe in four different ecotypes. In the mouse model, UCBPP-PA14 is as lethal as other well-studied P. aeruginosa strains. Mutations in the UCBPP-PA14 toxA, plcS, and gacA genes resulted in a significant reduction in pathogenicity in both… CONTINUE READING
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